The fine art of contract breeding
The quality of preclinical research is key to the successful translation of new drugs to the clinic. An important driver of this quality is a healthy, meticulously managed, and accurately...
Not all surgical models are equal: the beauty is in the details
Surgically modified animal models play a critical role in biomedical research, allowing researchers to mimic the structural and functional properties of human conditions. However, it is only with...
Progress in diets to induce nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, with ~24% of the US and European populations estimated to be affected. NAFLD is defined as the presence of fat in liver...
Patient-derived xenograft: making personalized medicine even more personal
It is well established that personalized medicine can overcome some limitations of a one-size-fits-all approach to healthcare. In research and practice, personalized medicine is being increasingly...
Cryopreservation and rederivation: Two steps forward, no setback
Effective colony management ensures reproducible research outcomes and adherence to the principles of the 3Rs. Cryopreservation and rederivation services are highly effective tools for meeting these...
How COVID-19 has changed the biomedical industry
The shift in research priorities due to COVID-19 has required rapid adjustment across the biomedical sector. The speed and effectiveness of this response supports our current scientific understanding...
How COVID-19 has affected the non-human primate shortage
Why is the shortage in non-human primates such a serious issue for the scientific community? Non-human primates (NHPs) are critical for clinical development pathways of new drug applications, but NHP...