Inotiv Blog

[safety pharmacology, toxicology, Telemetry, Safety Assessment, cardiovascular]

Understanding ICH E14/S7B Best Practices for Nonclinical Studies

The landscape of drug development requires a comprehensive approach to ensure safety, particularly concerning cardiac function. The ICH E14/S7B guidelines represent a significant step forward in...

[Safety Assessment, medical device testing, orthopedics, histopathology, medical device pathology, histology, pathology]

Healing Redefined: The Role of Bioabsorbable Implants in Modern Medicine

The growing field of biodegradable medical implants offers significant advantages, particularly in reducing the need for secondary surgeries and minimizing long-term complications that can arise from...

[Safety Assessment, mechanical testing, medical device testing, medtech, surgical support for medical device, orthopedics, device evaluation, histopathology, plastic pathology, preclinical research]

From Promise to Practice: Evaluating Magnesium-Based Medical Devices in Preclinical Studies

The growing field of biodegradable medical implants offers significant advantages, particularly in reducing the need for secondary surgeries and minimizing long-term complications that can arise from...

[Discovery, Safety Assessment]

Novel Polymer-Based Orthopedic Implant Shows Complete Integration, Healing, And Safety In A Multi-Year Sheep Study

Key Takeaways: Traditional inert and bioabsorbable orthopedic implants demonstrate several drawbacks, including inflammation or infection, often requiring follow-up surgeries. A biointegrative,...

[Genetic toxicology, Safety Assessment, In Vitro Cytogenetics, Genotoxicity, In Vitro Micronucleus]

Decoding the Revised OECD 487 Guideline: What Inotiv Clients Need to Know

Navigating the Latest Changes in In Vitro Micronucleus Testing and What It Means for YouKey Takeaways1. Spotlight on Test Guideline 487 Updates:Uncover key adjustments introduced in the updated...

[Safety Assessment, IBD, Crohn's, Colitis, Endoscopy]

Advantages of Non-Remitting Chronic IBD Models

The Advantages of Non-Remitting Chronic IBD Rodent ModelsAs the frequency of inflammatory bowel disease (IBD) increases globally, preclinical researchers continue to study new treatments that can...

[Animal welfare, Surgical models, Research services, Research models, Telemetry, Surgical Services]

Promoting Animal Welfare with Implanted Telemetry

As part of the advanced surgical services offered by Inotiv, telemetry represents an important part of a thoughtful, experimental design. Learn how telemetered data can promote animal welfare,...