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[Safety Assessment, Discovery and Translational Sciences]

Beyond Fragmentation: Inotiv’s Unified Tox Network Accelerates Discovery

Beyond Fragmentation: How Inotiv’s Unified Toxicology Network Accelerates Drug Development

[Animal Research, Research services, Research models, DIO]

Enhancing Health Monitoring with Sentinel Free Filter Testing (SiFT)

A healthy rodent colony is vital to the scientific integrity of research results, emphasizing the importance of monitoring colonies for pathogens. However, reliably detecting pathogens can be...

[Animal Research, Research services, Research models, DIO]

The expanding reach of GLP-1 research and the role of the diet-induced obesity (DIO) model

Glucagon-like peptide-1 (GLP-1) agonists, such as semaglutide and liraglutide, are major anti-obesity and anti-diabetes therapeutics that have produced clinically meaningful metabolic benefits. While...

[Discovery, psoriasis, disease models, inflammation, dermatology]

Strain Selection for IMQ-Induced Psoriasis Studies

The imiquimod (IMQ)-induced psoriasis model is widely used in preclinical dermatology research due to its ability to rapidly generate localized skin inflammation that resembles key features of human...

[Discovery, Safety Assessment]

Novel Polymer-Based Orthopedic Implant Shows Complete Integration, Healing, And Safety In A Multi-Year Sheep Study

Key Takeaways: Traditional inert and bioabsorbable orthopedic implants demonstrate several drawbacks, including inflammation or infection, often requiring follow-up surgeries. A biointegrative,...

[Genetic toxicology, Safety Assessment, In Vitro Cytogenetics, Genotoxicity, In Vitro Micronucleus]

Decoding the Revised OECD 487 Guideline: What Inotiv Clients Need to Know

Navigating the Latest Changes in In Vitro Micronucleus Testing and What It Means for YouKey Takeaways1. Spotlight on Test Guideline 487 Updates:Uncover key adjustments introduced in the updated...

[Discovery, IBD, Crohn's, Colitis, Endoscopy]

Advantages of Non-Remitting Chronic IBD Models

The Advantages of Non-Remitting Chronic IBD Rodent ModelsAs the frequency of inflammatory bowel disease (IBD) increases globally, preclinical researchers continue to study new treatments that can...

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